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Dr. Gregory Pais, ND
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Home arrow Blog arrow PREVENTING 600,000 CASES OF CANCER
PREVENTING 600,000 CASES OF CANCER

No, this isn't some thousand dollar a month chemotherapy drug or new surgical procedure. Hundreds of thousands of cases of cancer can be prevented for literally pennies a day.This new study looked at the relationship between serum levels of vitamin D and the risk of colon and breast cancer around the world and has estimated that 600,000 cases of breast and colon cancer could be prevented each year if vitamin D3 levels met the target proposed by researchers.

Cedric F. Garland, a cancer prevention specialist at the Moores Cancer Center at the University of California, San Diego (UCSD), estimates that 250,000 cases of colorectal cancer and 350,000 cases of breast cancer could be prevented worldwide by increasing intake of vitamin D3, particularly in countries north of the equator. Vitamin D3 is available through diet, supplements and exposure of the skin to sunlight.

"For the first time, we are saying that 600,000 cases of breast and colorectal cancer could be prevented each year worldwide, including nearly 150,000 in the United States alone," said study co-author Garland. The paper, which looks at the dose-response relationship between vitamin D and cancer, will be published in the August 2007 edition of the journal Nutrition Reviews.

The study combined data from surveys of serum vitamin D levels during winter from 15 countries. The data revealed an inverse association of serum vitamin D with risk of colorectal and breast cancer. The protective effect began at levels ranging from 24 to 32 nanograms per milliliter of 25-hydroxyvitamin D concentration in the serum. The 25-hydroxyvitamin D level is the main indicator of vitamin D status. The late winter average 25-hydroxyvitamin D in the US is about 15-18 ng/ml. The researchers maintain that increasing vitamin D levels in populations, particularly those in northern climates, has the potential to both prevent and possibly serve as an adjunct to existing treatments for cancer.

Previously studies by Garland and colleagues (Journal of Steroid Biochemistry and Molecular, February 2007) found that raising the serum 25(OH)D levels to 55 ng/mL was optimal for cancer prevention. This is the first study to recommend optimal vitamin D serum levels which, Garland said, are high enough to provide the needed benefit but which have been found by other scientists to be low enough to avoid health risks.

"This could be best achieved with a combination of diet, supplements and short intervals - 10 or 15 minutes a day - in the sun," said Garland. It could be less for very fair-skinned individuals. He went on to say "the appropriate dose of vitamin D in order to reach this level, could be very little in a lifeguard in Southern California... or quite a lot for someone in Northern Europe who tends to remain indoors most of the year."
 
The serum level recommended by the study would correspond to intake of 2000 International Units per day of vitamin D3 for a meaningful reduction in colorectal cancer. The researchers recommend 2000 IU/day, plus, when weather allows, a few minutes in the sun with at least 40% of the skin exposed, for a meaningful reduction in breast cancer incidence, unless the individual has a history of skin cancer or a photosensitivity disease.

Other studies have shown an association between higher levels of vitamin D3 or markers of vitamin D status and lower risk of cancers of the breast, colon, ovary, prostate and kidney. The researchers call for prompt public health action to increase intake of vitamin D3 as an inexpensive tool for prevention of diseases that claim nearly one million lives each year worldwide.

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